Breeding, Reproductive Health Advice, Shelter and Rescue Resources

30+ Things Not to Give Pregnant Dogs

Once your female dog is pregnant, what to feed a pregnant dog in her diet is even more important to keep an eye on. Using certain substances during a canine pregnancy can result in defects to the puppies.

Revival’s Director of Veterinary services, Dr. Greer recommends avoiding these substances during pregnancy:

  • Aspirin
  • Ciprofloxacin
  • Steroids including topicals in ear, eye and shampoo meds
  • Diethylstilbestrol
  • Doxycycline
  • Enrofloxacin
  • Estradiol
  • Excess Vitamin A
  • Excess Vitamin D
  • Progesterones before day 45
  • Prostaglandins
  • Gold
  • Griseofulvin
  • Metronidazole
  • Oxytetracycline
  • Non-steroidal anti-inflammatories such as Rimadyl and Metacam
  • Pentobarbital
  • Streptomycin
  • Sulfa’s such as Bactrim, Albon, Trimethoprim/Sulfa
  • Tetracycline
  • Testosterone
  • Warfarin


Can Topical Products Hurt a Pregnant Dog?

Certain topical products used on a pregnant dog can also cause defects in puppies. Those are:

  • Carbaryl
  • Dexamethasone Ophthalmic
  • Gentocin sprays
  • Mometamax
  • Ophthalmic with steroids
  • Pennyroyal
  • Rotenone
  • St. John’s Wort
  • TriTop ointment


Can a Pregnant Dog Have Steroids?

One additional thing to keep in mind is that there are many types of steroids and it’s impossible to list them all. Hydrocortisone is considered safe. Otherwise, always avoid any steroids when pregnant. This includes those that are applied topically and used on ears and eyes.

If you have additional questions on caring for a pregnant dog or what precautions should be taken for a pregnant dog, call us at 800.786.4751.

Will Your Dog Be Whelping Soon?

Revival’s Whelping Kit helps you easily shop for all your dog whelping supplies! We also have a wide variety of pregnancy supplies for dogs including prenatal vitamins, postnatal vitamins and calcium for whelping.

Whelping Kit Button

Written by: Marty Greer, DVM

Director of Veterinary Services

Marty Greer, Doctor of Veterinary Medicine, has 40+ years’ experience in veterinary medicine, with special interests in canine reproduction and pediatrics. She received her Doctor of Veterinary Medicine from Iowa State University in 1981. She’s served as Revival’s Director of Veterinary Services since 2019. In 2023, Dr. Greer was named the Westminster Kennel Club Veterinarian of the Year.

If you need help, call us at 800.786.4751.