Metoclopramide has been used in the treatment of gastric stasis disorders, gastroesophageal reflux, parvovirus, bilious vomiting syndrome and uremic gastritis. It is more effective in dogs as an antiemetic than a prokinetic agent, and it may not work well to protect cats from vomiting. Distinct differences in effectiveness and outcome are seen among various species.
Disposal of Unused Prescription Medications
- Return unwanted or unused medications to Revival Animal Health in person, or visit www.disposemymeds.org to find a pharmacy near you.
- A secondary method of drug disposal is to remove the unwanted medication from any wrappers or containers and place it in a plastic bag with moist coffee grounds or cat litter. This can be disposed of in the regular garbage collection.
- Please do NOT dispose of unwanted meds down the drain or toilet, as this may eventually find its way into the human water supply.
Learn more about disposal of unused prescription medications here
Disposal of Medical Sharps
- When you're finished with the syringe and needle, do not try to recap, remove, bend or break the needle. This is where most injuries occur.
- Dispose the syringe and needle immediately in a nearby sharps container. All sharps must be deposited in a puncture-proof container. Make sure your storage location is child and animal proof.
- As with all product handling, make sure you wash your hands after handling medical sharps.
Disposal of Sharps Container
- When your sharps container is half-full, sift dry Portland Cement throughout the sharps. Fill the container with water, and rotate until the cement is mixed and the sharps have been distributed throughout the cement mixture. Let cement dry for 24 hours.
- Seal the lid of the container tightly and use duct tape to seal. Label the container "Livestock Sharps" to properly identify the contents.
- Dispose of the containers in accordance with your state's regulations.
Our pharmacy hours are Monday-Friday 8:00 a.m. − 4:30 p.m. CST.
While infrequent, the most common side effects are changes in mental state or behavior. These include motor restlessness, involuntary spasms, aggression, hyperactivity and drowsiness or depression. It can increase detrusor muscle contractility and reduce bladder capacity.
Cats may display excitable behavior or appear disoriented. Both dogs and cats can become constipated.
Some effects observed in humans and possible in animals include: extrapyramidal effects, nausea, diarrhea, transient hypertension and elevated prolactin levels.
Metoclopramide is considered a class B drug during pregnancy, meaning it is safe to use during pregnancy if used cautiously. It is excreted in milk and may concentrate to about two times the plasma level; however, this does not appear to pose a significant risk to nursing neonates.
Metoclopramide is contraindicated in patients with GI hemorrhage, obstruction or perforation, as well as in those hypersensitive to it. Rule out these conditions before dosing. It is relatively contraindicated in patients with seizure disorders or head trauma. Metoclopramide may induce a hypertensive crisis in patients with pheochromocytoma.
Can cause prolactin release.
Due to its effects on aldosterone, use with caution if dosing to patients with congestive heart failure.
In patients with renal failure, a dosage adjustment may be required if using metoclopramide as a CRI. One reference suggests reducing the CRI by 25-50% of its standard dosage.
High doses are required for this medication to be lethal, and it is unlikely that an oral overdose will cause death in a veterinary patient. Clinical symptoms of overdose include sedation, ataxia, agitation, extrapyramidal effects, nausea, vomiting and constipation. Serotonin syndrome is possible.
Active Ingredient: Metoclopramide