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Easy Cat Deworming

Profender, made by Bayer HealthCare, is the world’s first broad-spectrum gastrointestinal worm treatment for cats with simple, stress-free, spot-on application. Profender gives effective control of every kind of intestinal worm normally occurring in cats without tablets or injection. A single dose effectively treats and controls infections caused by roundworms, removes larval and adult states of hookworms, and treats all tapeworms normally occurring in cats.

That’s right! A single, simple spot-on treatment is all it takes. Profender is applied topically to a single spot on the back of the cat’s neck. It really is that simple.


Profender not only keeps cats worm free, it also eliminates the stress of conventional worming treatment, for cats and owners alike. In fact, Profender makes worming so simple that it can be done while the cat is asleep. Existing products on the market to treat roundworms and tapeworms are intended solely for oral administration and are notoriously difficult for pet owners to use. Profender makes deworming easy for the owner, the veterinarian and the cat.

Profender has two active ingredients, emodepside and praziquantel. This topical solution is absorbed through the cat’s skin and then into the bloodstream. Blood travels to the intestine where the medications work on the parasites.


After the initial treatment, Profender should not need to be applied again. A second treatment is not necessary unless the pet is re-exposed and contracts a new infection. In this case, a second treatment can be re-applied after 30 days.

Do not apply Profender to broken skin or if the hair coat is wet. The application site will appear wet for a few hours and then will appear to have a dusty residue for a day or two after application. Oral ingestion or exposure should be avoided. Cats must not be allowed to lick the back of their necks for one hour. The product is very bitter tasting.


In a field study, 837 purebred or crossbred cats from single and multi-cat households were enrolled to evaluate safety and effectiveness under field conditions of use. Cats ranged in age from two months to 17 years and weighed between 0.8 pounds and 21 pounds. Data gathered from these studies demonstrated Profender Topical Solution to be safe and effective for the treatment and control of hookworm, roundworm and tapeworm.

There are currently three different sizes: the 2.2-5.5 lb small cat pack, the 5.5-11 lb medium cat pack, and the 11-17.6 lb large cat pack. Cats over 17.6 pounds should be treated with the appropriate combination of doses.

Profender requires a prescription and is approved for use in cats weighing more than 2.2 lbs and older than eight weeks. The safe use of Profender has not been evaluated in cats used for breeding, during pregnancy or in lactating queens. This product is labeled for cats only.

No more oral tablets. No more injections. With a pre-measured, simple, topical administration, you can feel confident your cats are getting the right dose. Stress free for cats. Stress free for you.

If you need help, call us at 1-800-786-4751.

-Dr. B
Don Bramlage, DVM, Director of Veterinary Services at Revival Animal Health

The materials, information and answers provided through this website are not intended to replace the medical advice or services of your personal veterinarian or other pet health care professional. Consult your own veterinarian for answers to specific medical questions, including diagnosis, treatment, therapy or medical attention.

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