Tri-Otic® Ointment treats canine ear infections caused by bacteria and yeast. It also reduces inflammation, pain, and itching and reduces ear wax production. It includes 3 active ingredients - betamethasone valerate, gentamicin sulfate, and clotrimazole that are a triple combination of steroid, antibacterial, and antifungal treatments.
Active Ingredient: Gentamicin sulfate, betamethasone valeate, and clotrimazole
Clinical and safety studies with gentamicin sulfate, betamethasone valerate, and clotrimazole have shown a wide safety margin at the recommended dose level in dogs.
Gentamicin: While aminoglycosides are absorbed poorly from skin, intoxication may occur when aminoglycosides are applied topically for prolonged periods of time to large wounds, burns, or any denuded skin, particularly if there is a renal insufficiency. All aminoglycosides have the potential to produce reversible and irreversible vestibular, cochlear, and renal toxicity.
Betamethasone: Side effects such as SAP and SGPT enzyme elevations, weight loss, anorexia, polydipsia, and polyuria have occurred folloing the use of parenteral or systemic cynthetic corticosteroids in dogs. Vomiting and diarrhea (occasionally bloody) have been observed in dogs and cats. Cushing's Syndrome in dogs has been reported in association with prolonged or repeated steroid therapy.
Clotrimazole: The following have been reported occasionally in humans in connection with the use of clotrimazole: erythema, stinging, blistering, peeling, edema, pruritus, urticaria, and general irritation of the skin not present before therapy.
The use of gentamicin-betamethasone-clotrimazole ointment has been associated with deafness or partial hearing loss in a small number of sensitive dogs. The hearing deficit is usually temporary. If hearing or vestibular dysfunction is noted during the course of treatment, discontinue use immediately and flush the ear canal thoroughly with a non-ototoxic solution.
Identification of infecting organisms should be made either by microscopic roll smear evaluation or by culture as appropriate. If overgrowth of nonsusceptible bacteria, fungi, or years occurs, of if hypersensitivity develops, treatment should be discontinued and appropriate therapy instituted.
Disposal of unused prescription medications:
- Revival Animal Health participates in the Take Away Environmental Return System which provides an environmentally safe destruction program.
- The preferred method of drug disposal is to return the unwanted product to a pharmacy that participates in the Take Away Environmental Return System. Seek a local pharmacy that participates in this program for safe disposal.
- A secondary method of drug disposal is to remove the unwanted medication from any wrappers or containers and place it in a plastic bag with moist coffee grounds or cat litter. This can be disposed of in the regular garbage collection.
- Please do NOT dispose of unwanted meds down the drain or toilet, as this may eventually find its way into the human water supply.
Disposal of medical sharps:
- When you're finished with the syringe and needle, do not try to recap, remove, bend or break the needle. This is where most injuries occur.
- Dispose the syringe and needle immediately in a nearby sharps container. All sharps must be deposited in a puncture-proof container. Make sure your storage location is child and animal proof.
- As with all product handling, make sure you wash your hands after handling medical sharps.
Disposal of sharps container:
- When your sharps container is half-full, sift dry Portland Cement throughout the sharps. Fill the container with water, and rotate until the cement is mixed and the sharps have been distributed throughout the cement mixture. Let cement dry for 24 hours.
- Seal the lid of the container tightly and use duct tape to seal. Label the container “Livestock Sharps” to properly identify the contents.
- Dispose of the containers in accordance with your state’s regulations.
Our pharmacy hours are Monday-Friday 8:00 a.m. − 4:30 p.m. CST.