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Home > All Pet Supplies > Sentinel
Sentinel - 80150-941-701
Sentinel - 80150-941-701
Sentinel - 80150-941-701
Sentinel - 80150-941-701


  • Sentinel® Flavor Tabs® provides multi-parasite protection for dogs
  • Once a month oral treatment for Heartworm disease, fleas, roundworms, hookworms and whipworms
  • Breaks the life cycle of fleas at both the egg and larval stages
  • Kills heartworm larvae before clinical signs can occur

This product is available by prescription only.
How to Order Prescription Medications
Prescription Authorization Form (PDF)
Please Note:
*Due to federal and state law, we cannot accept returns on prescription items.
*Revival Animal Health is licensed to sell prescriptions in 47 states. Click here Click here to see the state list.
Sentinel® Flavor Tabs® is a once a month oral medication that protects dogs and puppies against Heartworm disease (Dirofilaria immitus) and fleas, with additional protection against the three most common intestinal worms: roundworms, hookworms and whipworms. Each tablet is formulated to provide a minimum of 0.23 mg/pound (0.5 mg/kg) of Milbemycin Oxime and 4.55 mg/pound (10 mg/kg) body weight of Lufenuron. Milbemycin Oxime eliminates the tissue stage of heartworm larvae and the adult stage of hookworm (Ancylostoma caninum), roundworm (Toxocara canis, Toxoascaris leonine) and whipworm (Trichuris vulpis) infestations when administered orally according to the recommended dosage schedule. Lufenuron, the other active ingredient, is an insect development inhibitor which breaks the flea life cycle by inhibiting egg development. The concurrent use of an approved adulticide such as Capstar® Tablets (Nitenpyram) may be needed to provide a flea management system that kills adult fleas and prevents flea eggs from hatching especially if dogs have repeated exposure to flea infested environments or animals.

Sentinel® Flavor Tabs® are available in in four tablet sizes and formulated according to the weight of the dog. Each tablet size is available in color-coded packages of 6 tablets per package.

Brown: 2-10 lbs
Green: 11-25 lbs
Yellow: 26-50 lbs
White: 51-100 lbs
Active ingredients: Milbemycin Oxime and Lufenuron

Store in a dry place at controlled room temperature, between 59° and 77°F (15-25°C).
Well tolerated at the veterinarian's recommended dosage.
Side Effects:
The following adverse reactions have been reported in dogs after giving Milbemycin Oxime or Lufenuron: vomiting, depression/lethargy, pruritus, urticaria, diarrhea, anorexia, skin congestion, ataxia, convulsions, hypersalivation and weakness.
There are no known food or drug interactions, and Sentinel® is considered safe in pregnant and lactating animals.

Do not use in puppies less than four weeks of age and less than two pounds of body weight.

Prior to administration of Sentinel® Flavor Tabs®, dogs should be tested for existing heartworm infections. Infected dogs should be treated to remove adult heartworms and microfilariae prior to initiating treatment with Sentinel® Flavor Tabs®. Mild, transient hypersensitivity reactions manifested as labored respiration, vomiting, salivation and lethargy have been noted in some treated dogs carrying a high number of circulating microfilariae. These reactions are presumably caused by release of protein from dead or dying microfilariae.

Sentinel® Flavor Tabs® immediately break the flea life cycle by inhibiting egg development. However, pre-existing flea populations may continue to develop and emerge after treatment with Sentinel® Flavor Tabs® has begun. Based on results of clinical studies, this emergence generally occurs during the first 30-60 days. Therefore, noticeable control may not be observed until several weeks after dosing when a pre-existing infestation is present. Cooler geographic areas may have longer lag periods due to a prolonged flea life cycle. The concurrent use of an approved adulticide, like Capstar® may be employed depending on the severity of the infestation.
If a Sentinel® Flavor Tabs®-treated dog comes in contact with a flea-infested environment, adult fleas may infest the treated animal. These adult fleas are unable to produce viable offspring. The temporary use of an adulticide product may be necessary to kill these adult fleas.
The safety of the concurrent use of Sentinel® Flavor Tabs® and Capstar® Tablets in pregnant or nursing dogs or in puppies less than 11 weeks of age has not been demonstrated.

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Keep out of the reach of children
Recommended Dosage Schedule
Body Weight
Milbemycin Oxime
per Tablet
per Tablet
2 to 10 lbs
2.3 mg
46 mg
11 to 25 lbs
5.75 mg
115 mg
26 to 50 lbs
11.5 mg
230 mg
51 to 100 lbs
23 mg
460 mg

For concurrent dosing of Sentinel® Flavor Tabs® and Capstar® Tablets, see package insert.

Sentinel® Flavor Tabs® are palatable and most dogs will consume the tablet when offered by the owner. As an alternative to direct dosing, the tablets can be hidden in food. Be certain the dog consumes the entire tablet or tablets. Administer Sentinel® Flavor Tabs® to dogs, immediately after or in conjunction with a normal meal. Food is essential for adequate absorption of Lufenuron. Watch the dog closely following administration to be sure the entire dose has been consumed. If it is not entirely consumed, redose with the full recommended dose as soon as possible.
Sentinel® Flavor Tabs® must be administered monthly, preferably on the same date each month. Treatment with Sentinel® Flavor Tabs® may begin at any time of year. In geographic areas where mosquitoes and fleas are seasonal, the treatment schedule should begin one month prior to the expected onset and should continue until the end of “mosquito and flea season.” In areas with year-round infestations, treatment should continue through the entire year without interruption.
If a dose is missed and a 30-day interval between dosing is exceeded, administer Sentinel® Flavor Tabs® immediately and resume the monthly dosing schedule. If Sentinel® Flavor Tabs® replace daily diethylcarbamazine (DEC) for Heartworm prevention, the first dose must be given within 30 days after the last dose of DEC.

Product Reviews
By: Sentinel
From: Oxford,Wi
I have asked my vet numerous times for the wormer she recommended a couple of years ago. She said it was stopped being made. But when I typed in the active ingrediant Sentinel came up. It is such a relief to know this is still being made by someone. The convienance of giving this to adult dogs is unbelievable. It is a VERY GOOD wormer in all respects.

Thank You so much for having it to buy.

Leetta % Have a Heart
Read more reviews
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For over 25 years, Revival Animal Health has been caring for people who care for pets by delivering quality, reliable products, along with customer service that's committed to your needs. Owners, breeders and shelters count on us because we too love pets, and provide the knowledge, understanding and genuine care it takes to keep them happy and healthy. We feel this is truly what it means to serve you with Pet Care from the Heart®.

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